Palmatine chloride

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Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. Palmatine chloride, a naturally occurring photosensitizer isolated from traditional Chinese medicine (TCM), can induce remarkable cell apoptosis, significantly increase intracellular ROS level and significantly kill breast cancer MCF-7 cells; it also has potential in photodynamic therapy on colon adenocarcinoma.

Palmatine chloride has anti-C. albicans effect, the effect is mainly influenced by the growth rate constant (k(2)) and maximum power output P(m)(2) of phase II; it mixes with berberine hydrochloride elicit antifungal activities and could be used to treat M. canis in rabbits. The quenching mechanism of palmatine hydrochloride (PMT)on bovine hemoglobin (BHb) is a static process, the electrostatic force played an important role in the conjugation reaction between BHb and PMT. Palmatine chloride treatment can reduce blood sugar and oxidative stress in STZ induced diabetic rats.

Formula: C21H22ClNO4

CAS Number: 10605-02-4

Molecular Weight: 387.87

Purity: 99.8% 

Appearance: Solid

Research Chemicals are available in Crystalline solid, solid, crystal, powder, and liquid form

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