Norfluoxetine Hydrochloride

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Fluoxetine Hydrochloride is the hydrochloride salt form of fluoxetine, a diphenhydramine derivative and selective serotonin reuptake inhibitor with antidepressant, anti-anxiety, antiobsessional and antibulimic activity and with potential immunomodulating activity. Upon administration, fluoxetine binds to the presynaptic serotonin (5-HT) receptor resulting in negative allosteric modulation of the receptor complex, thereby blocking the recycling of serotonin by the presynaptic receptor.

Inhibition of serotonin reuptake by fluoxetine enhances serotonergic function through serotonin accumulation in the synaptic space, resulting in long-term desensitization and downregulation of 5-HT receptors, preventing 5-HT-mediated signaling and leading to antidepressant, anti-anxiety, antiobsessional and antibulimic effects. In addition, fluoxetine may inhibit the expression of pro-inflammatory cytokines, including interleukin-6 (IL-6). This may prevent IL-6-mediated inflammation and cytokine storm.

The toxicity and long-term health effects of recreational Norfluoxetine Hydrochloride use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.

Formula: C16H16F3NO•HCl

CAS Number: 57226-68-3

Molecular Weight: 331.76

Purity: 99.8% 

Appearance: Research Chemicals are available in Crystalline solid

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